De novo long read genome and transcriptome assemblers GoldRush and RNA-Bloom2, published in Nature Communicationsnews ·
Our de novo long read genome assembler, GoldRush, and reference-free long read transcriptome assembler, RNA-Bloom2, were published today. Please refer to the GoldRush Nat. Commun. and RNA-Bloom2 Nat. Commun. manuscripts, respectively. The GoldRush long read assembler marks a paradigm shift in long read de novo assembly of large genomes, generating highly contiguous assemblies using an order of magnitude less RAM than state-of-the-art Overlap-Layout-Consensus long read assemblers. RNA-Bloom2 is a reference-free assembler for long-read transcriptome sequencing data that requires a fraction of the peak memory and runtime needed by a competing method.